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diagnosis rheumatology neurology syndrome erythematosus lupus ringenhancing systemic algorithm autoimmune bee behcet cerebritis chondroma clinical coccidioides coccidioidomycosis disease fungal immune
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... : • CNS Lymphoma ... #Brain #differential
Algorithm for evaluating multiple ring-enhancing lesions in immunocompetent (HIV negative) #ringenhancing #lesions #cns #brain #diagnosis #differential #algorithm
ring-enhancing lesions ... #cns #brain #diagnosis ... #differential # ... algorithm #causes ... #radiology #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #CNS #neurology ... cerebritis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... collaboration • CNS ... Syndrome #diagnosis #management
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... nervous system (CNS ... LHON) plus MRI lesions ... noninflammatory #differential
Intraarticular Chondroma - MSK Radiology Imaging Findings: • Subtle soft-tissue infrapatellar mass seen obscuring Hoffa's fat pad.
Intraarticular Chondroma - MSK ... Radiology Imaging ... Case description ... growth with symptoms ... Differential diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Bilateral signs and/or symptoms ... Disorders: - SLE ... Myelitis #diagnosis #management ... #neurology #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... permanent alopecia Differential ... • May involve PNS ... and CNS • Headache ... Induced Lupus: • Symptoms
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... phenomenon (16%) MSK
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... • Progressive symptoms ... tract, and often causes ... chorioretinitis, CNS
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