10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... , Seizure disorders ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... deficiencies - PNH ... Associated - SLE ... #Diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Arthritis • SLE ... Pulmonary Disease Neurologic ... • Somatization Disorder
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Clinical evidence of (fatigue ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... • May involve PNS
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup ... and Differential ... Neurologic disorders ... #causes #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... in primary or secondary ... Vasculitis - Collagen disorders ... Autoimmune Vasculitis (lupus ... deficiency Work
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Better call hematology ... some time, let’s see ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Symptoms: • Fatigue ... DDX: Rule Out Secondary ... blood count with differential ... Syndromes #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... : • Fevers • Fatigue ... affects the skin, neurologic ... tract, and often causes