13 results
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
/ Breakthrough DVT ... APLS - MPN/PNH ... Structural - Pelvic masses ... #VTE #anticoagulation ... #hematology #differential
Causes of Breakthrough/Extension of Thrombosis and Management Algorithm

#Anticoagulation #Breakthrough #Thrombosis #Algorithm #Extension #VTE #DVT #Hematology #Management
Causes of Breakthrough ... Thrombosis and Management ... Algorithm #Extension #VTE ... #DVT #Hematology ... #Differential #Causes
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
DVT = deep vein ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... and incidental DVT ... without concomitant DVT ... Anticoagulation #Management ... #Hematology #Oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology ... #anemia
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 • Superficial Venous Thrombosis
 • Upper
Upper Extremity DVT ... Thrombophilia • Cancer ... DeLoughery @Bloodman #VTE ... anticoagulation #duration #management ... #DVT #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... SJIA], systemic lupus ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... to cold IgG • Lupus ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Isolated distal DVT ... Unprovoked proximal DVT ... therapy - Second VTE ... Treatment #Algorithm #management ... #hematology #anticoagulation
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Lymphoma or other cancers ... gastric and breast cancer ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology