12 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... patterns (this case ... #Clinical #MRI ... #Brain #Diagnosis ... #Radiology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... nervous system (CNS ... neuropathy (LHON) plus MRI ... lesions and clinical
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... Case description ... • PVNS/Giant Cell ... #clinical #Radiology ... diagnosis #msk #rheumatology
Central Pontine Myelinolysis - Magnetic resonance imaging of the brain revealed a central area of high
imaging of the brain ... signaling in the pons ... #Clinical #Radiology ... #Neuro #MRI #Central ... Demyelination #Syndrome
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... - MRI: inflammation
If you haven't seen it, flecainide can cause significant yellowing of the skin and eyes.
flecainide can cause ... #flecainide #cutaneous ... #sideeffects #clinical ... #photo #nails # ... cardiology #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Strong sign of cutaneous ... oligoclonal bands • MRI ... tract, and often causes ... (lower legs), cutaneous ... aphthous ulcers, cutaneous
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... skin (xerosis) • Cutaneous ... Nephrogenic DI Hematologic