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diagnosis differential clinical cutaneous management antimda5 antimda5dm antinxp2 antinxp2dm arterial autoimmune cardiology discoloration embolism eschar fingernails flecainide leukemia mucormycosis myopathy
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ulcerations • Skin ... ulcerations • Auricular skin ... • Skin vasculopathies ... #rheumatology # ... dermatology #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... blisters containing pus ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... have typical DM skin ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... CLL -> Invade Skin ... #Leukemia #Hematology
If you haven't seen it, flecainide can cause significant yellowing of the skin and eyes.
flecainide can cause ... yellowing of the skin ... sideeffects #clinical #photo ... #nails #cardiology ... #dermatology #discoloration
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
immunosuppressed pts ... steroid use Dx: skin ... Mucormycosis #Eschar #dermatology ... #skin #clinical ... #photo
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... aspiration > 50% of pts ... statins - probably caused ... Myositis #Myopathy #rheumatology
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