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diagnosis management differential algorithm anemia anticoagulation aplastic behcet breakthrough cardiology cerebritis cns dermatology disease dvt erythematosus lupus neurology oncology pericarditis
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Recurrent / Breakthrough ... APLS - MPN/PNH ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Puncture, EEG Treatment ... #neurology #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral Ulcerations: Recurrent ... three episodes of recurrent ... Arthritis, AS Treatment ... glucocorticoids • Recurrent ... signs #symptoms #rheumatology
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... manifestations, TREATMENT ... diagnosis #management #treatment ... #rheumatology # ... cardiology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Neutropenia - recurrent ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... blisters containing pus ... Rule out other causes ... and lower jaw Treatment ... #Rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
respiratory tracts • Recurrent ... tract, and often causes ... : Recurrent oral ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Recurrent inflammation ... Criteria: • Recurrent ... hearing loss, nausea ... affected tissue Treatment ... Polychondritis #rheumatology
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