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neurology differential management rheumatology clinical mri syndromes cerebritis crypto cryptococcal erythematosus inflammatory leigh lesions meningitis noninflammatory ringenhancing sjogrens sle systemic
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... affecting the brain ... nervous system (CNS ... Inflammatory causes ... • Systemic lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... - Compatible syndrome ... + toxo IgG • CNS ... 30% present w/ CNS ... #causes #radiology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
BEE Syndromes - ... Non-inflammatory Causes ... affecting the Brain ... nervous system (CNS ... with aura #BEE
Leigh Syndrome History: 19-month-old girl with hypotonia, developmental delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... elevation (can be ... patterns (this case ... Clinical #MRI #Brain ... #Diagnosis #Radiology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
6th Decades (can be ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... histopathologic changes in LNs ... Histopathological Diagnoses ... is thought to be ... agonists #TAFRO #diagnosis
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... low glucose) CNS ... Nausea & vomiting ... meningitis #T2 #MRI #Brain ... #clinical #radiology
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