12 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute ... Management #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Tumor lysis syndrome ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
An acute rise or ... hypertension and no other risk ... disturbance, or acute ... 109 mm Hg) with clinical ... apnea: CPAP, most pts
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
• Sepsis Complications ... • Increased risk ... Diagnoses: • Acute ... Coronary Syndrome ... #cardiology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... subthalamic nuclei, pons ... • DWI+ in acute ... patterns (this case ... #Clinical #MRI
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
increased infection risk ... to 8 years Clinical ... noninfectious complications ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... effusion, INC risk ... Nephrogenic DI Hematologic ... Malignancy Risk
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: • Acute ... Clinical Features ... • May involve PNS ... Thrombosis highest risk