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diagnosis anthracycline biostatistics cardiotoxicity chemotherapy emergencies epidemiology formulas hemeonc leukemia oncologic pharmacology toxicity usmle
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL (Acute Lymphoblastic ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
USMLE Epidemiology and Biostatistics Summary Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Proves cause-effect ... = incidence in acute ... but not on the causal ... - Rishi Kumar, MD ... Biostatistics #formulas #calculations
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... LVEF) can occur acutely ... HER2 agents cause ... Cardiotoxicity #cardiology ... #oncology #pharmacology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology ... AML (~20 %) and APL
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