30 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Findings Risk ... Apolipoprotein E4 allele Risk ... chromosome 21) Signs ... / Symptoms / Complications
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Faget's Sign & Liebermeister's ... Dissociation EVERY 1 F RISE ... Beta Blockers • CNS ... • Drug Fever CLINICAL ... #Fagets #Sign #Pulse
Kussmaul's sign in Constrictive Pericarditis 

A 50-year-old woman with a remote history of mediastinal lymphoma (age
the paradoxical rise ... Causes = RV failure ... pericarditis (this case ... PhysicalExam #Video #Clinical ... Pericarditis #Cardiology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
immunocompetent population Risk ... symptoms, unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
An acute rise or ... hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs ... apnea: CPAP, most pts
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... kinase (BTK) Complications ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... involvement: Intractable nausea ... pain • Extra-CNS ... complications ( ... neurology #symptoms #signs
Kussmaul's Sign and Friedreich's Sign on Neck Examination

A middle-aged M with unknown PMH presents with dyspnea.
Kussmaul's Sign ... the underlying cause ... Kussmaul's (JVP rise ... #PhysicalExam #Clinical ... #Video #Cardiology