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diagnosis rheumatology management neurology radiology algorithm erythematosus lesions lupus ringenhancing systemic treatment autoimmune cardiomyopathy cerebritis clinical crypto cryptococcal leukemia meningitis
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... #differential # ... diagnosis #causes
Algorithm for evaluating multiple ring-enhancing lesions in immunocompetent (HIV negative) #ringenhancing #lesions #cns #brain #diagnosis #differential #algorithm
ringenhancing #lesions #cns ... #brain #diagnosis ... #differential # ... algorithm #causes ... #radiology #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #CNS #neurology ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... • May involve PNS ... and CNS • Headache ... Thrombosis highest risk
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... circulation = risk ... Better call hematology ... some time, let’s see ... JAK2 V617F) and MPNs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... ruled out • Brain ... MRI: Check for brain ... Disorders: - SLE ... management #neurology #differential
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... , LE edema • Minority ... of Pts: cardiogenic ... diagnosis #management #cardiology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... tract, and often causes ... chorioretinitis, CNS ... #Diagnosis #Rheumatology
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