15 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... thrombosis and/or blood-brain
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
affecting the brain ... Inflammatory causes ... syndrome • Systemic lupus ... optica spectrum disorder ... #inflammatory #differential
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
and Metabolic Brain ... Inhalation Central Pons ... #Disorders #Clinical ... #Differential # ... Diagnosis #Radiology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... • May involve PNS ... vein thrombosis Hematologic ... Thrombosis highest risk
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... An acute rise or ... 109 mm Hg) with clinical ... Neurologic disorders ... #Differential #
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Mitochondrial disorder ... patterns (this case ... Leigh #Syndrome #Clinical ... #MRI #Brain #Diagnosis ... #Radiology
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
from the brain ... may mimic an LMN disorder ... form part of the differential ... syndromes are clinically ... very different clinical
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... ruled out • Brain ... MRI: Check for brain ... management #neurology #differential
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... Clinical • Under-recognized ... • Minority of Pts ... diagnosis #management #cardiology