24 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
affecting the brain ... an underlying autoimmune ... Inflammatory causes ... optica spectrum disorder ... #inflammatory #differential
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
CNS: parietal ... lobe • Retina • Systemic ... encephalitis) • Brain ... • Psychiatric disorders ... diagnosis #neurology #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... thrombosis and/or blood-brain
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... : Brain tumor ... • Infectious: Brain ... necrotizing myopathy • Autoimmune
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
: • Valvular disorders ... Myeloproliferative disorders ... with an increased risk ... • Increased risk ... #cardiology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... (CNS) involvement ... an underlying autoimmune ... noninflammatory #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... deficiencies • Autoimmune ... • May involve PNS ... Thrombosis highest risk
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... to have a "wood-grain ... multiforme • Acute systemic ... comparison #table #differential ... #diagnosis #dermatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Hypocomplementemia • Can cause ... effusion, INC risk ... Nephrogenic DI Hematologic ... Malignancy Risk