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diagnosis differential clinical management skinrash antinxp2 cryofibrinogenemia dermatomyositis embolism gangrenosum herpes nonpalpable palpable pathophysiology purpura pyoderma shingles sjogrens syndrome thrombosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Acquired Risk ... Testosterone - Coumadin skin ... coagulation and other causes ... - Vasculitis ... pathophysiology #hematology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
resulting in a vasculitis ... which causes slowly ... ulceration of the skin ... Images #Clinical #Photo ... #Dermatology #SkinRash
Herpes Zoster: Herpes virus mediated infection that occurred in this patient receiving chemotherapy for an underlying
vessicles in this case ... superimposed bacterial ... skin infection, ... Images #Clinical #Photo ... #Dermatology #SkinRash
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... cryoglobulins • Negative causes ... to medium-sized arteries ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
May develop in pts ... syndrome • Coronary arteries ... tract, and often causes ... Thrombosis and arterial ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
effusion, INC risk ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Malignancy Risk ... Sjogrens #Syndrome #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Muscle atrophy may cause ... three days #AntiNXP2DM ... diagnosis #management #rheumatology ... #dermatology
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