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diagnosis differential clinical management antinxp2dm arterial cellulitis dermatomyositis embolism gangrenosum infection legs monoclonal nonpalpable oncology palpable paraproteinemias pathophysiology purpura pyoderma
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
resulting in a vasculitis ... which causes slowly ... ulceration of the skin ... Images #Clinical #Photo ... #Dermatology #SkinRash
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Acquired Risk ... Testosterone - Coumadin skin ... coagulation and other causes ... - Vasculitis ... pathophysiology #hematology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
Vibrio Vulnificus skin ... necrotic ulcers Risk ... hemochromatosis, hemolytic ... rash #cellulitis #dermatology ... legs #clinical #photo
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Amyloidosis (CVS+PNS ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
effusion, INC risk ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Malignancy Risk ... Sjogrens #Syndrome #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Muscle atrophy may cause ... three days #AntiNXP2DM ... diagnosis #management #rheumatology ... #dermatology
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