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diagnosis differential rheumatology algorithm management systemic generalized hemolytic intravascular oncology pruritus secondary agglutinin antinxp2 antinxp2dm atlas basics clinical coagulation cold
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... - Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia •
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... Mycosis fungoides (cutaneous ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology ... Diagnosis #Algorithm #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Causes == Primary ... Skin Lesions == ... renal failure/uremia ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /Quantity: • Primary ... - Hemolytic anemia ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgM) (e.g. primary ... differential #diagnosis #hematology ... #anemia
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... scabitic mite or by cutaneous ... lesions that contain pus ... #Diagnosis #Dermatology ... #Skin #Primary
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... the context of primary ... • May involve PNS ... neuropathy • Transverse ... lymphopenia, low PLT • Anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... presentation) • Cutaneous ... • Symptoms of anemia ... • hemolytic anemia ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... Paraproteinemias #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic
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