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differential dermatology localized alopecia diffuse lymphadenopathy management rheumatology aplastic clinical cutaneous dyspnea erythematosus eschar infections infectiousdiseases leukemia lupus mcv monoclonal
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... ) #Diffuse #Focal ... Lymphadenopathy #LAD ... #Algorithm #Causes ... #Hematology #Oncology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... deficiency • Lead ... PK, HbC, HbSS, PNH ... #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... #Localized #Focal ... Lymphadenopathy #LAD ... #Algorithm #Causes ... #Hematology #Oncology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Heart failure - CAD ... - Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia •
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Algorithm DIFFUSE ... - Secondary to Skin ... #HairLoss #Alopecia ... #Diagnosis #Algorithm ... #causes
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required - Infectious
Focal / Localized ... Algorithm Scarring ... - Secondary to Skin ... Secondary syphilis #HairLoss ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... Hypocellular/Hypoplastic MDS ... #oncology #hematology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... • May involve PNS ... neuropathy • Transverse ... lymphopenia, low PLT • Anemia
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
lacrimal glands: • Focal ... Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic
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