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diagnosis differential pain approach erythematosus lupus management sle syndrome systemic vasculitis workup autoimmune classification clinical dermatology gout gouty leukemia monoarthritis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Lyme), reactive arthritis ... Like in this case ... SLE, psoriatic arthritis ... #Joint #Pain #MSK ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... • Inflammatory arthritis ... Noninflammatory arthritis ... with rheumatoid arthritis ... #Pain #MSK #rheumatology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... with joint-space ... • PVNS/Giant Cell ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... in small joints ... Leucopenia/lymphopenia, Thrombocytopenia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
constitutional symptoms ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... #Diagnosis #MSK ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... nonerosive inflammatory arthritis ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
: • Joint pain ... • May involve PNS ... neuropathy • Transverse ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... bone pain, fever, joint ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... • Progressive symptoms ... tract, and often causes ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
peripheral neuropathy, transverse ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology
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