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diagnosis differential management lupus polycythemia sle anemia classification comparison disorders druginduced dyspnea eosinophil eosinophilia erythrocytosis hemolytic pulmonary sjogrens sob syndrome
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... - Water - Pus ... Pulmonary HTN - Vasculitis ... Barre - ALS - Transverse ... myelitis • Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... for specific symptoms ... 1,500 cells/µL Workup ... Differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • May involve PNS ... neuropathy • Transverse ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... platelet decrease - PNH ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Differential Diagnosis Algorithm ... Splenomegaly, Increased PMNs ... Chronic Chest Symptoms ... #Causes #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... constitutional symptoms ... Systemic Lupus Erythematosus ... comparison #table #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... ischemia • Skin: Erythematous ... • Progressive symptoms ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... JAK2 V617F) and MPNs ... about secondary causes ... #workup #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
peripheral neuropathy, transverse ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... Sjogrens #Syndrome #Rheumatology
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