14 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... Lesions == Macules ... Lesion / Systemic ... Myelodisplastic syndrome ... #causes
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... SAPHO syndrome ( ... Eosinophilic folliculitis ... Sweet syndrome ... #Lesions #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... blisters containing pus ... lesions + Rheumatic ... Rule out other causes ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... : - Genetic lesions ... - Hepatitis, eosinophilic ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • (Peripheral eosinophilia ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... amyloidosis, PAH Skin ... Nephrogenic DI Hematologic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
lesions • Mononeuritis ... • EGPA: - Eosinophilia ... tract, and often causes ... • Cogan Syndrome ... Ocular inflammatory lesions-interstitial