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diagnosis dermatology differential rheumatology management systemic algorithm oncology pruritus secondary vasculitis anemia antinxp2 antinxp2dm aplastic arterial atlas autoimmune basics classification
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Causes == Primary ... Skin Lesions == ... Skin Lesion / Systemic ... Myelodisplastic syndrome
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... SAPHO syndrome ( ... Eosinophilic folliculitis ... Acute generalized ... Sweet syndrome
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
Lesions Primary ... considered to be caused ... that contain pus ... or part of a generalized ... #Skin #Primary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... /Quantity: • Primary ... Kasabach-Merritt syndrome ... deficiencies - PNH
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Skin involvement ... SJS/TEN • Acute Generalized ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Myelodisplastic syndrome ... secondary #systemic #generalized ... Diagnosis #Algorithm #causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Vaginal dryness • Primary ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... blisters containing pus ... lesions + Rheumatic ... Rule out other causes ... #Rheumatology #
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