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diagnosis differential dermatology rheumatology clinical management oncology rash secondary systemic algorithm cellulitis comparison generalized infectiousdiseases pathophysiology pruritus pulmonary table vasculitis
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Diagnosis- Compatible syndrome ... , may also see skin ... splenomegaly Other infections ... Infectious: ... differential #diagnosis #causes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
parvovirus B19 infection ... parvovirus B19 infection ... Amyloidosis • Eosinophilic ... Antiphospholipid-antibody syndrome ... lesions • Discoid
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia •
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... deficiencies - PNH
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Lesions == Macules ... Lesion / Systemic ... renal failure/uremia ... Myelodisplastic syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... : - Genetic lesions ... - Hepatitis, eosinophilic ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... SAPHO syndrome ( ... Eosinophilic folliculitis ... Sweet syndrome ... #Lesions #Differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Goodpasture syndrome ... cell arteritis Infections ... diseases • Fungal infections ... rash #diagnosis #rheumatology
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics Cellulitis: Deep skin and subcutaneous fat infection Pseudo
Cellulitis: Deep skin ... Angioedema • Sweet syndrome ... Sarcoidosis • Eosinophilic ... • Compartment syndrome ... #dermatology #skin
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