18 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... #diagnosis #management ... signs #symptoms #rheumatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... SAPHO syndrome ( ... Eosinophilic folliculitis ... Sweet syndrome ... #Lesions #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Skin involvement ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory disease Skin ... for refractory lesions ... or refractory lesions ... #Treatment #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... lesions + Rheumatic ... Rule out other causes ... diagnosis #management ... #Dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... : - Genetic lesions ... - Hepatitis, eosinophilic ... #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic ... Diagnosis #Management