9 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... erythematosus #signs ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... Rheumatologic Disease ... Joint #pain #Differential ... #Diagnosis #MSK
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... vesicular eruption - Joints ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... by neutrophilic autoimmune ... insufficiency - Joints ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... • Progressive symptoms ... tract, and often causes ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... #Myositis #Myopathy
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... • Non-autoimmune ... rheumatologic diseases ... Induced Lupus: • Symptoms
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... #Rheumatology #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... • Bilateral signs ... and/or symptoms ... • Infectious causes ... - Sjogren - Vasculitis