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management hematology lysis tls acromegaly chronic cll differential emergencies endocrinology hemeonc leukemia leukostasis lymphocytic neurology oncologic weakness
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Initial workup ... of the above Treatment ... #diagnosis #management ... #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... • Pathophysiology ... #TLS #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... full infectious work-up ... days → add fungal work-up ... antibiotics TLS (tumor-lysis ... #HemeOnc #Diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... system: Brain tumor ... Infectious: Brain abscess ... Lack of UMN/LMN signs ... dystrophies Work
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
pancreatic islet cell tumor ... Beckwith Wiedemann syndrome ... and Workup: • ... Endocrinology #Treatment ... #Pathophysiology
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