10 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... • Mechanism: Exchanges ... aspiration #Potassium #Binding ... #pharmacology #table ... #comparison #binders
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... causes prolonged PR ... #EKG #ECG #Changes ... #Progression #Table
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... potassium and ECG changes ... waves, Prolonged PR ... , asystole #hyperkalemia
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... injury, etc) ECG changes ... waves, prolonged PR
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, ST depress, ↑PR ... Elimination (see Table ... Treatments: • K-Binding ... Resins - Exchanges ... SPS (15-60g PO/PR
Intern Pocket Cards - Inpatient Blood Pressure Management Guide
ß-blockers:
 • Metoprolol, Carvedilol, Labetalol
 • Bradycardia, heart
Valsartan • AKI, hyperkalemia ... inhibitor use Calcium Channel ... #pharmacology #table ... agents #internship #comparison
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
the Treatment of Hyperkalemia ... , changes on ECG ... , severe hyperkalemia ... Figure 3 is an algorithm ... , and Table 3 summarizes
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
GABA-mediated chloride ion channel ... GABA-mediated chloride ion channel ... Antagonists: - Blocks binding ... #pharmacology #comparison ... #table
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
-60y (hormonal changes ... hyperphosphatemia, hypercalcemia ... incidental CXR finding ... Self-limiting, chronic but stable