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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... Agents - Dr. ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat ... • Mechanism: Exchanges ... #pharmacology #table ... #comparison #binders
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... waves, prolonged PR ... removal of offending agent
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
maximum daily dose ... require phosphate binding ... agents since they ... are not able to ... restricted due to hypercalcemia
Intern Pocket Cards - Inpatient Blood Pressure Management Guide
ß-blockers:
 • Metoprolol, Carvedilol, Labetalol
 • Bradycardia, heart
Valsartan • AKI, hyperkalemia ... inhibitor use Calcium Channel ... #pharmacology #table ... #agents #internship ... #comparison
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, ST depress, ↑PR ... Elimination (see Table ... Transient, repeat dose ... Treatments: • K-Binding ... SPS (15-60g PO/PR
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
GABA-mediated chloride ion channel ... GABA-mediated chloride ion channel ... Antagonists: - Blocks binding ... #pharmacology #comparison ... #table
Atrial Fibrillation RVR - Medications
Diltiazem
 • Preferred in patients with chronic lung such as Asthma and
of or increased doses ... beta-blockers and calcium-channel ... beta-blockers and calcium-channel ... management #treatment #comparison ... #table
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
- Any adverse events ... event, follow ACC algorithm ... Change in clinical ... if result will change ... postoperative cardiac events