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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Vaughan Williams Classification ... - Summary Table ... III agents - Potassium ... #Medications #Classification ... #Summary #Table
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... depolarization • ↑ PR ... 3 - Potassium Channel ... velocity) - ↑ PR ... #Pharmacology #Classification
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... and ECG changes ... waves, Prolonged PR ... #potassium #high
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... DrEricStrong #Hypokalemia ... Diagnosis #Low #Potassium ... #Table #Classification ... #Causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... • Mechanism: Exchanges ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #pharmacology #table
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... prolonged PR and ... wave to produce classic ... #Progression #Table
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... depolarization • ↑ PR ... 3 - Potassium Channel ... velocity) - ↑ PR ... #Pharmacology #Classification
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... waves, prolonged PR ... treatment Remove potassium
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
eliminate excess potassium ... reduce dietary potassium ... , changes on ECG ... Figure 3 is an algorithm ... , and Table 3 summarizes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, ST depress, ↑PR ... Elimination (see Table ... Treatments: • K-Binding ... SPS (15-60g PO/PR ... Management #Treatment #potassium