8 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... Endocarditis, Aortic ... valve lesions Abdominal ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... and branches • GCA ... Presentation - Systemic Symptoms ... purpura: strong sign ... , and SLE) • Urinalysis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... or sed rate): Value ... very remarkable w/differential ... #Temporal #Signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Disorders: - SLE ... - Sjogren - Vasculitis ... management #neurology #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... purpura: Strong sign ... < 30 years • Aorta ... tract, and often causes
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Involves aortic ... • Autoimmune (SLE ... Marantic (NTBE) Differential ... valvular disease • Vasculitis ... block, annular or aortic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Kikuchi disease • Type-I ... • Transverse Myelitis ... Cytopenias • Cardiac valve ... Induced Lupus: • Symptoms
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... , involves aortic ... • Autoimmune (SLE ... valvular disease • Vasculitis ... block, annular or aortic