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diagnosis differential infections infectiousdiseases causes brain abscess aids aspergillus betadglucan biomarkers cardiology cd4 comparison endocarditis evaluation galactomannan hiv hivaids mycoses
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... (Histoplasma, Cryptococcus ... failure, COPD, Lung ... • CD4 < 200: Pulmonary ... ABG, BDG, Serum Cryptococcal
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... Toxoplasmosis • Fungi ... Mucormycosis, Cryptococcus ... #Infections #Concurrent
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Negative: Cryptococcus ... infection (IFI) ... surfaces - Infections ... decreased with: concurrent ... setting of GVHD) ID
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... Mucormycosis, Cryptococcus ... #Infections #Concurrent
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... Mucormycosis, Cryptococcus ... #Infections #Concurrent
Nocardiosis - Nocardia spp Pathogen: Filamentous gram-positive branching rod, grows in acid fast staining and anaerobic conditions Clinical
involved) 32% • Pulmonary ... Primary site of infection ... 9%, up to 20% lung ... Nocardia #diagnosis #management ... #microbiology #
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management ... polymicrobial infection ... Prevotella • Fungal ... Dermatitidis - Cryptococcus ... #Abscess #pulmonary
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... ), MAI, Cryptococcal ... Pseudomonas FUNGAL ... #Infections #HIV ... #AIDS #pulmonary
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... Hypercoagulable (APLAS) Microbiology ... Aspergillus • Cryptococcus ... Cerebral > Splenic, pulmonary ... Endocarditis #diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fluconazole CRYPTOCOCCUS ... CSF and serum Cryptococcal ... change in the lungs ... nails, bronchi, lungs ... #Diagnosis #Management
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