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diagnosis blood product reactions emergencies hemeonc hemophagocytic lymphohistiocytosis oncologic oncology transfusion transfusions treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
acute or subacute febrile ... following: • Fever ... rapidly, and empiric antibiotic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... deficiency) • Post ... coagulopathy & ↑bleeding ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Mediated: - Febrile ... deficiency) - Post ... coagulopathy & ↑bleeding ... Transfusions #diagnosis #management ... #hematology #reactions
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
work-up - If febrile ... 500 → may stop antibiotics ... syndrome): - Hematologic ... Simultaneous clotting and bleeding ... (hours-to-days post-infusion
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