101 results
diagnosis differential treatment hematology causes rheumatology infections microbiology oncology classification clinical indications algorithm pharmacology summary workup blood chagas dermatology endocrinology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... extramedullary disease ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... • Peripheral smear ... cells can indicate disease ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... hematopoietic cell ... ) Up to 50% of PTLD ... #Post #Transplantation ... oncology #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Cold-induced symptoms - most ... IgM) • Blood smear ... Polyclonal IgM post ... malignancies -> CLL
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... manifestations: • Most ... azathioprine (for post ... #Syndrome #Treatment ... #management #pharmacology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... Hemolytic anemia, Post ... intoxication, Post-splenectomy ... Hemolytic uremic syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... cold agglutin disease ... antibiotics are the most
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Defects: Sickle cell ... Electrolytes: Wilson's disease ... Peripheral Blood Smear
Post-Intensive Care Syndrome (PICS) Symptoms of PICS: - Physical Domain: Generalized weakness, Fatigue, Difficulty walking - Cognitive
Post-Intensive Care ... Syndrome (PICS) ... Domain: Anxiety, PTSD ... titration (RASS) #Post ... PICS #diagnosis #management
Problem Representation - Approach to the Infectious Disease Patient Who: Patient age and host/risk factors (such as
the Infectious Disease ... Patient age and host ... define the clinical syndrome ... febrilepodcast@gmail.com #InfectiousDiseases
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