21 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
IDSA Algorithm for ... the Management ... oral antibiotic treatment ... or those with clinical ... #cellulitis #idsa
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... GrepMed Handbook Clinical ... up to 10w post-ABx ... - produced by all ... continue Tx for 7d post-Abx
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... weeks without infection ... microglobulin Treatment ... workup #oncology #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... in those with CLD ... months without treatment ... Coagulation Failure Infections ... By Tina Hang
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
- IDSA Guidelines ... micafungin) for most ... Venous Catheters (CVL ... or TEE unless clinical ... #candidiasis #treatment
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most ... immunophenotype Clinical ... Complications: 1) Infection ... uw_IMresidency #CLL ... hemeonc #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... presentation, and most ... Low or absent NK cell ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... other cancers: Most ... and M panel Management ... #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... Diagnosis: • Clinical ... Bayesian approach for post-test ... D/c all heparin ... #Treatment #Hematology