21 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... chemotherapy, anti-CD20 (PTLD ... #management #treatment
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... haploidentical>unrelated>HLA ... symptoms, unexplained hematologic ... #Post #Transplantation ... #management #transplant
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... presentation, and most ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... By Tina Hang ... Failure #Cirrhosis #Hepatology ... #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
and Management ... GrepMed Handbook Clinical ... infection up to 10w post-ABx ... continue Tx for 7d post-Abx ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Cyclosporiasis - Diagnosis and Management Summary
Pathogen: 
 • Cyclospora cayetanensis
 • Foodborne, waterbone, and soil-transmitted.
 •
and Management ... routine O&P • Clinical ... Treatment: • TMP-SMX-DS ... #management #treatment ... #microbiology #
Spinal Epidural Abscess - Illness Script
Epidemiology:
 - Patients at risk for bacteremia: IVDU, dental abscess, HD
Alcoholism, DM, HIV Microbiology ... - Staph aureus most ... common (63%) Clinical ... imaging as needed Treatment ... #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
: • Clinical Suspicion ... Bayesian approach for post-test ... non-heparin A/C if clinical ... #Management #Treatment ... #Hematology #HemeOnc