9 results
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... #differential #diagnosis ... #dermatology #nails ... #table #lines
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... #differential #diagnosis ... #dermatology #nails ... #table #lines
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
disorders • Diagnosis ... Matthew Ho, MD PhD ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Syndrome (MAS) ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... with excessive macrophage ... Diagnosis via genetic ... #management #treatment ... #hematology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... Generalized itchy rash ... SAPHO syndrome ( ... Sweet syndrome ... #Dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Criteria for Diagnosis ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... • A clinical diagnosis ... #Rheumatology # ... diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... termed MAS-HLH: Macrophage ... Activation Syndrome ... #Management #Hematology