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diagnosis differential management algorithm hodgkins liver lymphoma acute agglutinin aplastic causes classification cold comparison gap globulin hemeonc hemolytic hemophagocytic hepatitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... C, A, E, B, D, EBV ... , 1° PSC, Cystic ... Sophia_Hayes_MD #Liver #Injury ... Acute #algorithm #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... to BM) • Constitutional ... Parvovirus B19 - EBV ... Epstein-Barr virus (EBV ... #oncology #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Venoocclusive disease ... HBV, HCV, HEV, EBV ... Hereditary: Wilson Disease ... intestines, white blood cells ... diagnosis #algorithm #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV), EBV ... type (B cell, T cells ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... - Mycoplasma, EBV ... sensitize red blood cells ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Weight loss • Anemia ... number of sites of disease ... classification #hematology ... #oncology #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - Blood & BM • ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Heavy chain disease ... acute HIV, HBV, EBV ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Infections (e.g., EBV ... ▪ Autoimmune diseases ... - Cytopenias (anemia ... and CD8+ T cells ... Diagnosis #Management #Hematology
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