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Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... blood (measured on ABG ... Low SvO2 → Low PaO2 ... sepsis) - High PaO2
ABG vs VBG: Arterial vs Venous Blood Gases ABG PROS: Tells you exactly what the arterial environment looks
ABG vs VBG: Arterial ... Blood Gases ABG ... looks like (pH, PaCO2 ... serial exams #ABG ... Comparison #pH #pCO2
What's in a Blood Gas? VBG vs ABG BOTTOM LINE: VBG is less painful, more easily obtained
VBG vs ABG BOTTOM ... LINE: VBG is less ... obtained than ABG ... EBM #Diagnosis #ABG ... Comparison #PH #PCO2
Markers of Organ Dysfunction in Severe Sepsis Altered consciousness Confusion Psychosis Tachycardia Hypotension Altered CVP Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... <70mmHg SaO2 < ... 90% PaO2/FiO2 300%
Perform computations online at: ScyMed.com 6th ED ICU-card «ICU, Formulas & Drugs» HEMODYNAMIC PATTERNS Condition SAP CVP PAP PCWP CO C(a-v)02 PVR SVR Hypovolemic shock ↓ ↓ ↓ ↓ ↓ ↑ ↑ ↑ Cardiogenic shock ↓ 1 ↑ 1 1 ↑ Septic shock ↓ ↓ ↓ ↓ ↑ ↓ ↓ ↓ Cardiac Tamponade . ↑ ↑ 1 ↓ → ↑ RV
Index CARDIAC WORK ... RCWI Cardiac Work ... 0.0144 Cardiac Work ... Ventricular Stroke Work ... age-corrected PAO2
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
Arterial Blood Gas (ABG ... Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... Arterial #BloodGas #ABG
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... (Patm - 47) - (PaCO2 ... /0.8)] - PaO2 Simplified ... /0.8)] - PaO2 Normal
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
ABG And BMP Normal ... 7.35-7.45 • PaCO2 ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... Summary #Nephrology #ABG
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis 1) Start with the Anion Gap (AG). 2)
the Anion Gap (AG ... Do you need an ABG ... approximates an ABG ... and ~5 mmHg to pCO2 ... Disorders #Evaluation #workup
Arterial Blood Gas (ABG) Interpretation • AG/non-AG Metabolic Acidosis • AG Acidosis "Delta/Delta" • Metabolic Alkalosis
Arterial Blood Gas (ABG ... Interpretation • AG ... /non-AG Metabolic ... Acidosis • AG ... Arterial #BloodGas #ABG
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