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PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A

- Approach to Acid-Base ... pH L - Labs: PCO2 ... PLACO #AcidBase #Acid

Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
• ↓ H+ (↑

+ (↑ pH) • ↓ PCO2 ... tissue): • ↑ H+ (Acid ... ) • ↑ PCO2 •

Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all

Acid Base Disorders ... CI-, HCO3-, PH, pCO2 ... 3: Look at the pCO2 ... . 3a: If pCO2 ... joshsteinbergMD #Acid

Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
• Metabolic Acidosis (HCO3 < 24mmol/L) CO2

Acid-Base Disorders ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2

Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the

Acid Base Compensation ... variables (pH, HCO2, pCO2

Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?

Interpretation and Acid-Base ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... Amy Chung, MD, MSc

Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation:
1. Acidemia or Alkalemia?
2.

Acid Base Disorders ... 7.35-7.45 • PaCO2 ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... ABG #bloodgas #Acid

#ICUCard
RENAL
GFR
90-131
mL/min
((140-age)*Wt)/(72*Cr)
Glomerular Filtration Rate (Cockcroft)
CI Cr
90-131
mL/min
(CrU * volume)/CrS
Creatinine Clearance
FENa
0.0-1.0
%
((U/P Na)/(U/P Cr))*100
Fractional Excretion of Na+
Na req
mEq
(125-Na)*0.6*Wt
Required Sodium
FE Urea

Osmolar Gap ACID-BASE ... H_def 0 mEq Acid ... pCO2 = 1.5 (HCO3 ... )/HCO3 Acid base ... 100% mask A-a

Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the

Acid Base and Blood ... 2. pCO2 - What’s ... the pCO2?

Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS)
- Respiratory symptoms must have begun within one

week of a known clinical ... inspired oxygen (PaO2 ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2 ... H2O - Severe - PaO2

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