52 results
Markers of Organ Dysfunction in Severe Sepsis 
Altered consciousness 
Confusion 
Psychosis 

Tachycardia 
Hypotension 
Altered CVP 
Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... <70mmHg SaO2 < ... 90% PaO2/FiO2 300% ... Severe #Sepsis #CriticalCare
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2 ... Interpretation #AcidBase
PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A
pH L - Labs: PCO2 ... jadav_md #PLACO #AcidBase
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2, pCO2 ... Diagnosis #Nephro #AcidBase
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... < 35 mmHg) #AcidBase
ABG vs VBG: Arterial vs Venous Blood Gases

ABG
PROS: Tells you exactly what the arterial environment looks
looks like (pH, PaCO2 ... #Correlation #Comparison ... #pH #pCO2 #Diagnosis
Hypoxemia vs Hypoxia
Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal
Hypoxia - Insufficient oxygen
arterial oxygen (PaO2 ... compensate for low PaO2 ... differential #diagnosis #comparison
PROSEVA definition of ARDS
Thus, the PROSEVA trial essentially modifies the Berlin definition of ARDS, with the
requirement that the PaO2 ... requires that the PaO2 ... #Diagnosis #CriticalCare
Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... MD @nickmmark #acidbase
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) 
- Respiratory symptoms must have begun within one
inspired oxygen (PaO2 ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2 ... H2O - Severe - PaO2 ... Criteria #Diagnosis #CriticalCare