363 results
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... Low SvO2 → Low PaO2 ... sepsis) - High PaO2 ... #differential #diagnosis
Markers of Organ Dysfunction in Severe Sepsis 
Altered consciousness 
Confusion 
Psychosis 

Tachycardia 
Hypotension 
Altered CVP 
Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... 90% PaO2/FiO2 300% ... Protein C #Diagnosis ... #CriticalCare #Diagnosis
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... Interpretation #AcidBase ... #Diagnosis #Compensation
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Simplified ... /0.8)] - PaO2 Normal ... #differential #diagnosis
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
- Differential Diagnosis ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... < 35 mmHg) #AcidBase ... #Differential #Diagnosis
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2, pCO2 ... #Diagnosis #Nephro ... #AcidBase #Acidosis
PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A
pH L - Labs: PCO2 ... jadav_md #PLACO #AcidBase ... #Acid #Base #diagnosis
ABG vs VBG: Arterial vs Venous Blood Gases

ABG
PROS: Tells you exactly what the arterial environment looks
looks like (pH, PaCO2 ... #Correlation #Comparison ... #pH #pCO2 #Diagnosis
Hypoxemia vs Hypoxia
Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal
Hypoxia - Insufficient oxygen
arterial oxygen (PaO2 ... compensate for low PaO2 ... #differential #diagnosis ... #comparison #pulmonary
Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... MD @nickmmark #acidbase ... workup #algorithm #diagnosis