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Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -

Respiratory Acidosis + Alkalosis ... pH ↓ pCO2 ↓ ... ↑ - Metabolic alkalosis ... Respiratory alkalosis ... Compensation #acidosis #alkalosis

Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
• Metabolic Acidosis (HCO3 < 24mmol/L) CO2

Respiratory Acidosis (pCO2 ... • Metabolic Alkalosis ... • Respiratory Alkalosis ... (pCO2 < 35 mmHg

Blood Gas Analysis and Interpretation
STEPS TO ANALYSIS
1. Look at PH. Alkalotic or acidotic?

Alkalotic or acidotic ... - If alkalotic, ... then it is an alkalosis ... - pCO2 (respiratory ... component) - alkalotic

Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the

2. pCO2 - What’s ... the pCO2? ... production Respiratory alkalosis ... Salicylates Metabolic Alkalosis ... - Contraction alkalosis

Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all

CI-, HCO3-, PH, pCO2 ... has a primary alkalosis ... . 3a: If pCO2 ... >40 patient's alkalosis ... is -Y patient's alkalosis

Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation:
1. Acidemia or Alkalemia?
2.

7.35-7.45 • PaCO2 ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... ↑ ↑ Metabolic alkalosis ... Acidosis ↑ ↓ Resp Alkalosis

Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?

acidosis or an alkalosis ... Look at the pCO2 ... the change in pCO2 ... concomitant respiratory alkalosis ... Metabolic #Acidosis #Alkalosis

Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the

variables (pH, HCO2, pCO2 ... AcidBase #Acidosis #Alkalosis

Hepatopulmonary Syndrome
HPS - Diagnosis:
1. Patients with liver disease
2. Alveolar-arterial oxygen gradient (AaP02) >15 mmHg

Moderate HPS: ≥ 60 PaO2 ... Severe HPS: ≥ 50 PaO2 ... Very severe HPS: PaO2 ... Syndrome #diagnosis #management

Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)

more acidotic or alkalotic ... and ~5 mmHg to pCO2 ... • Metabolic Alkalosis ... • Respiratory Alkalosis ... Diagnosis #acidosis #alkalosis

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