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Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
O2 is inspired) PAO2 ... hypoxia) - Low PaO2 ... Low SvO2 → Low PaO2 ... Low SvO2 → Low PaO2 ... Hypoxemia #summary #pulmonary
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Normal ... Intracardiac, Pulmonary ... V/Q Mismatch: Pulmonary
Perform computations online at:
ScyMed.com
6th ED
ICU-card
«ICU, Formulas & Drugs»
HEMODYNAMIC PATTERNS
Condition
SAP
CVP

PAP PCWP

CO C(a-v)02 PVR

SVR
Hypovolemic shock
↓
↓
↓
↓
↓
↑
↑
↑
Cardiogenic shock
↓
1
↑
1

1
↑

Septic shock
↓
↓
↓
↓
↑
↓
↓
↓
Cardiac Tamponade
.
↑
↑
1
↓

→
↑
RV
→ ↓ → →↑ Pulmonary ... +2PDP)/3 Mean Pulmonary ... MPAP-WP)*79.92)/CO Pulmonary ... = 1.36 cmH20 PULMONARY ... age-corrected PAO2
Platypnea-Orthodeoxia Syndrome on Physical Exam
The case of a patient with a diagnosis of cirrhosis and platypnea-orthodeoxia
Physical Exam The case ... there is a drop in SaO2 ... to 90% (and in paO2 ... #respiratory #pulmonary
PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A
Approach to Acid-Base ... pH L - Labs: PCO2 ... AcidBase #Acid #Base
Hypoxemia vs Hypoxia
Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal
Hypoxia - Insufficient oxygen
arterial oxygen (PaO2 ... compensate for low PaO2 ... diagnosis #comparison #pulmonary
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) 
- Respiratory symptoms must have begun within one
consistent with pulmonary ... lung collapse, or pulmonary ... inspired oxygen (PaO2 ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2
Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
Acid Base Disorders ... CI-, HCO3-, PH, pCO2 ... 3: Look at the pCO2 ... . 3a: If pCO2 ... joshsteinbergMD #Acid #Base
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
Acid Base Compensation ... variables (pH, HCO2, pCO2