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management hematology neurology oncology symptoms agglutinin algorithm arteritis autoimmune behcet chronic classification cll cold disorders erythematosus gca giantcell hemolytic hemophagocytic
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Clinical Presentation ... anemia • Cold ... chills, flank pain ... #hematology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... matter, spinal cord ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... age, however the disease ... : HLH signs and
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... Infections: - ... , Scleroderma, Systemic ... MCTD, Sjogren syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... - Clinical Presentation ... • Pain in LN ... number of sites of disease ... Treatment • Early
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... or without back pain ... • Bilateral signs ... Transverse Myelitis Treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... very remarkable w/differential ... vs infection vs ... complaints- anemia ... them, but urgent rheumatology
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