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differential causes primary acute cholangitis chronic gastroenterology hodgkins injury leukemia lfts lymphoma pbc summary syndrome abnormal aclf aflp alkaline alp
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
Disease (Cirrhosis ... ) - Complications ... #Cirrhosis #Complications ... #diagnosis #management ... #summary #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Liver biopsy findings ... #Cirrhosis #Diagnosis ... #Algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Highest • Bone • Liver ... Bone symptoms - Pain ... #Algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... (± cirrhosis) w ... disease, liver ... #Hepatology #gastroenterology ... #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential Diagnosis ... hepatitis, Acute biliary ... , Sickle Cell, VOD ... Causes #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... /Liver failure ... or higher • Liver ... #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
vomiting, abdominal pain ... ↓Antithrombin Ill ... Monitor and Treat Complications ... #Pregnancy #hepatology ... #management #pathophysiology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... failure • Primary biliary ... #Algorithm #Hepatology
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