16 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sensitivity to pain ... Signs and symptoms ... stimulation Clinical ... Treatment: • ... #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... and Symptoms: ... bile ducts Differential ... cholestasis, Primary sclerosis ... #workup #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
C’s of Primary Sclerosing ... asymptomatic at diagnosis ... Care focuses on symptom ... remain subject to clinical ... #Hepatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... likely it will be clinically ... Primary Biliary Cirrhosis ... #diagnosis #differential
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... symptoms can mimic ... #management #treatment ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... vomiting, abdominal pain ... infiltration) Differential ... Diagnosis: Viral ... Liver #Pregnancy #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... fasciculations Common Symptoms ... conditions listed in differential ... Treatment: - Multidisciplinary ... #management
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... & Symptoms: • ... inflammatory) • joint pain ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... effusions, weight gain ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
shunt (Type 2) Clinical ... with or without cirrhosis ... resolution of symptoms ... #management #treatment ... #hepatology