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differential erythematosus lupus sle systemic ana antinuclear autoimmune behcet classification fungal infections infectiousdiseases mycoses myopathy myositis neurology patterns polychondritis relapsing
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... salivary ducts Clinical ... #Syndrome #Rheumatology ... #Diagnosis #Management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... , Sjögren Syndrome ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... (20%) Renal disease ... #symptoms #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, AS Treatment: ... Nonsurgical abdominal pain ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Presentation - Systemic Symptoms ... purpura: strong sign ... C-ANCA) pattern: antibodies ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren ... Joint pain • Swan ... • Transverse Myelitis ... Induced Lupus: • Symptoms ... #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... • Bilateral signs ... and/or symptoms ... Treatment: • ... #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
papules and Gottron sign ... ) • Shawl sign ... of aspiration pneumonia ... • Nonerosive arthritis ... #Myopathy #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
vasculitis - Infectious ... IGG4 - Hepatic cirrhosis ... and the systemic symptoms ... Hypoalbuminemia Treatment ... #management #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Sudden onset of pain ... Most common • Sjogren ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
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