10 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... , Sjögren Syndrome ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... salivary ducts Clinical ... #Syndrome #Rheumatology ... #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, AS Treatment: ... Nonsurgical abdominal pain ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
paresthesia, abdominal pain ... filling +++ (risk of pulmonary ... #syndrome #diagnosis ... #management #timeline ... #treatment #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... them, but urgent rheumatology ... #Symptoms #Diagnosis ... #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... : HLH signs and ... #management #treatment ... #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... and the systemic symptoms ... Hypoalbuminemia Treatment ... #management #rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Sudden onset of pain ... Most common • Sjogren ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptomsRheumatologic ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... Meningitis, septic arthritis ... #Management #Infections