29 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... tumor • Non-bloody ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... during childhood ... prematurely • risk of joint ... deficiency • blood ... (muscle/joint)
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... cases there are ... cell disease Rheumatology ... discrepancy, multiple joint ... Peds #Pediatrics #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... #Diagnosis #MSK ... #rheumatology #
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Differential Diagnosis ... Water - Pus - Blood ... Guillain Barre - ALS ... Transverse myelitis • Hematology ... Deconditioning - Pain
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... family history - Medications ... plateletcount), peripheral blood ... not required in all ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... • Peripheral blood ... uncovered incidentally during ... #Differential #diagnosis ... #hematology #eosinophilia
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... Diagnosis: ... • Rule out other ... causes such as ... SAPHO #Syndrome #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... search ANA and aPL ... has been ruled out ... erythematosus #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... pain/Night sweats ... #msk #physicalexam