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differential arthritis erythematosus msk sle systemic workup algorithm approach causes classification comparison degenerative dermatology diabetes disease hematology inflammatory jointdisease jointpain
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain ... painful swelling -> Pain ... after > 1 hr • Blood ... Rheumatoid arthritis, Lupus ... JointDisease #JointPain #Diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... tumor • Non-bloody ... #Joint #Pain #MSK ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... lesions Abdominal pain ... Glomerulonephritis Myositis(5%) Blood ... signs #symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Arthritis: • Joint ... pain • Swan neck ... activation and/or medications ... #Rheumatology
Metformin: Biguanide Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
the first-line medication ... effective in lowering blood ... The main counseling ... point for side ... #Metformin #Pharmacology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... lesions • Severe pain ... Immunosuppressed • New medication ... Autoimmune Vasculitis (lupus ... #dermatology #physicalexam
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... mass • Rapidly rising ... , fever, joint pain ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... such as systemic lupus ... pulses, bruis, or blood ... Large Vessel: Blood ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... Polyarthritis: • Blood ... : • Complete blood ... , and low back pain
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