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diagnosis dermatology rheumatology petechiae classification management ascorbicacid cryoglobulins ddxof dermatologic dermpath glomerulonephritis granulomatosis lesions manifestations nonpalpable nutrition pathology physicalexam progressive
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Petechial/Purpuric ... purpura. ... or purpuric rash ... #Petechiae #Purpural ... #Purpuric #Rash
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... , Palpable purpura ... • Palpable purpura ... Vesicles overlying purpuric ... purpura • Mixed
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Schonlein Purpura ... Rash: - Purpura ... #Petechiae #Rash
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... #Petechiae #Purpura ... #Palpable #Algorithm ... #Differential #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... - Microscopic polyangiitis ... - EGPA - GPA
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Purpura Anti-GBM ... #differential # ... diagnosis #algorithm
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... Identification of causes ... hemopathies (4%) • Cryoglobulinemia ... lesions #diagnosis #clinical ... pathology #lesions #differential
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... triad of Palpable ... purpura, Arthralgia ... polyangiitis ... purpura) • Cutaneous
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... Schonlein Purpura ... erythematous nodules, purpura ... purpura: strong ... purpura.
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: • Purpura, ischemic ... purpura: Strong ... purpura • Pauci ... purpura, joint ... ) • Palpable purpura
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